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Embryo series courtesy of Einhard Schierenberg. This mechanism of FoxO regulation is conserved in C. Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans. Furthermore, this finding suggested that mobilizing the power of C.
Autophagy and lipid metabolism coordinately modulate life span in germline-less C. Nonetheless, it is likely that the extent of these interactions is not yet fully appreciated. Hyperactive neuroendocrine secretion causes size, feeding, and metabolic defects of C. Insulin binding causes a conformational change that induces autophosphorylation, activating intrinsic receptor tyrosine kinase activity Luo et al. Nothing in this Agreement shall be construed as creating a joint venture, agency, partnership, trust or other similar association of any kind between the parties hereto.
Request for this document already exists and is waiting for approval. Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans.
AES E-Library Complete Journal Volume 48 Issue 4
Asymmetric arginine dimethylation determines life span in C. In parallel, the labs of Klass and Johnson isolated and characterized the first long-lived C. The use of the genetically tractable system, C. The Drosophila cytohesin ortholog Steppke was identified as a gene required for larval growth Fuss et al. Non-ageing developmental variant of Caenorhabditis elegans.
Functional divergence of dafachronic acid pathways in the control of C. Genetic analysis of age-dependent defects of the Caenorhabditis elegans touch receptor neurons. Your request has been submitted for approval. The conserved gene Melted was identified in a gain-of-function screen for genes that affect cell growth in Drosophila Teleman et al.
In both mammalian cells and C. Evolution of Shc functions from nematode to human. Please allow business days for a response. Pkinase inhibition induces dauer formation, thermotolerance and longevity in C.
They are resistant to a diverse array of stresses, including heat Lithgow et al. Continuous Sensor Monitoring.
Identification by machine vision of the rate of motor activity decline as a lifespan predictor in C. Moreover, many of the downstream transcriptional targets that control these processes have been identified. Genetic and pharmacological factors that influence reproductive aging in nematodes.
From key regulator genes to disposable soma. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. During larval development, the C. Chemosensory neurons function in parallel to mediate a pheromone response in C. High-throughput in vivo analysis of gene expression in Caenorhabditis elegans.
The observation that mammalian G-protein-coupled receptors can act as receptors for the relaxin family of insulin-related peptide hormones Hsu et al. In fact, many of the organismal phenotypes studied in C. Genes that regulate both development and longevity in Caenorhabditis elegans. Some alleles exhibit additional defects in development, behavior, fat storage, and reproduction Gems et al.
Extended longevity in mice lacking the insulin receptor in adipose tissue. Targeting X chromosomes for repression. The mir targets that are important for life span control are not known.
This Agreement may be executed in counterparts, each of which shall be deemed to be an original, les lymphomes pdf and which together shall constitute one and the same agreement. Positive selection of Caenorhabditis elegans mutants with increased stress resistance and longevity.
The somatic reproductive tissues of C. Interacting genes in nematode dauer larva formation. This interaction is required for resistance to heavy metals Mizuno et al.
The dauer-defective mutant daf was identified as the C. Here we review the discovery of the C. To date, no candidates have emerged from genetic screens.
The main components of the C. Evolution of lifespan in C.
Two neurons mediate diet-restriction-induced longevity in C. Two insulin-like peptides antagonistically regulate aversive olfactory learning in C. Neuropeptide feedback modifies odor-evoked dynamics in Caenorhabditis elegans olfactory neurons. Inhibition of germline proliferation during C.
Complete Journal Volume 48 Issue 4
Autophagy links lipid metabolism to longevity in C. Catechin induced longevity in C. Activation of orphan receptors by the hormone relaxin.
Loss-of-function mutations in the C. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.
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